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Glucose is a simple sugar that your body likes. Your cells use it as a primary source of energy, so when you consume glucose, it's actually helpful. When it's transported into the body, it stimulates the pancreas to produce insulin. Your brain notices this increase, understands that it's busy metabolizing what you just ate, and tells you that you're less hungry. The important thing to note here is that when you consume glucose, your brain knows to tell you to stop eating when you've had enough.
For our purposes, high fructose corn syrup (HFCS) and sucrose are the same thing because they're both highly sweet and they both contain a large amount of fructose. Sucrose is 50% fructose and HFCS is 55% fructose (which is high compared to normal corn syrup, but pretty normal when compared to cane sugar). The remainder of each is glucose, which we discussed above. In most cases, fructose is bad for you because of how it's processed by the body. Fructose can only be metabolized by the liver, which is not a good thing. This means a greater number of calories—about three times more than glucose—are going through liver processes and that results in a much higher production of VLDL (the bad cholestoral mentioned earlier) and fat. It also results in a higher production of uric acid and a lot of other things you don't want, which is believed to lead to fun stuff like hypertension and high blood pressure.
Fruit contains fructose, but as any food pyramid or suggested intake ratios will tell you, fruit is okay. How is that possible if fructose is almost always bad? This is because fruit, in its natural form, contains fiber. Fructose doesn't provide a satiety alert to let your brain know to tell you to stop eating, but fiber does this to a high degree. This is why you can eat fruit—despite the fructose content—without experiencing the same problems as, say, drinking a sugary soda. This is why fruit can actually be beneficial. The same goes for processed sugar. Sugar doesn't exist naturally as sparkly white crystals, but as a really tough stick called sugar cane. It isn't until you process the sugar can that you lose all the fiber it contains. Without the fiber, you only have the tasty but problematic part of the original food. That's why processed sugars can cause problems.
Of anything you can do, this is the most important. Fructose-heavy soda is remarkably problematic because, for reasons discussed above, you can keep drinking it while your body isn't recognizing your sugar intake—so your body remains hungry. On top of that, a lot of soda (Coke is a great example) contains high amounts of sodium. Why would you want salt in your soda? You wouldn't, but it makes you thirsty and prompts you to buy more soda to drink, so it's great for the companies that make it. It also makes you pee (as does caffeine if your soda has that) so you'll feel the need to drink more as well. This is masked by simply adding more fructose to the drink, which is another obvious problem.
As previously mentioned in the section about processed and unprocessed foods, fiber is very necessary in curbing sugar intake. It does what fructose can't do, and that's alert you that you've consumed calories and you don't need to eat anymore. Basically, fiber and fructose need to work together. Fiber is fructose's unattractive but brilliant friend. Fructose makes up for fiber's lack of sweetness while fiber makes up for fructose's uselessness.
If you like dessert, don't keep it at home. This is obvious, but it's also one of the most effective options (you can't eat something you don't have). If you really want it, make yourself do a little work. Have dinner, and if you have a craving for dessert afterwards then go out and get some. Chances are it won't take more than 20 minutes for that craving to die, as you'll fill up and won't want to eat anything else. In the event it doesn't, go out and buy a reasonably-sized dessert. As long as you're not inclined to do this regularly, prolonging the decision to eat dessert should help you out.
Your metabolism pretty much goes in the toilet when you don't move around at all, making sitting the harbinger of death. We're big on standing desks, which, for starters, helps your burn far more calories than sitting. It's just good for you all-around. As with any level of physical activity, from standing to walking to running, calorie burn is a poor focus to have. Going for a 20-minute run is about equal to two thin mint cookies (unless you're really fast, in which case you might get a third cookie). Burning off a fast food meal would require exercising for most of your day. It's just not feasible for anyone. Physical activity helps because it reduces stress (which reduces appetite) and improves the way your metabolism functions (so less fat is produced when processed by your body). These things are much more important than calorie burn.
Standing up is a good way to negate the effects of sitting down but you might not be able to do it all the time. If you can't, make sure you get up and walk around at least every 30 minutes. If you just don't want to stand up while you work, try doing it for only an hour a day. It's a short amount of time and is better than nothing. Regardless of how much you sit, keep track of the time and try to engage in physical activity—even if it's as mild as walking around—for as close to that amount of time as possible. Go for walks (or walk instead of drive), play a sport, exercise, clean the house, or do anything that keeps you moving around. Generally the entertainment you consume while sitting (television and movies) can still be consumed while you're standing or moving around. This may not be your ideal situation, but it's a good way to increase your physical activity without giving up a normally sedentary activity you enjoy.






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